Innovation Research

Healthcare And Health Technology Economics


Pietzsch JB. Richter A-K, Randerath W, Steffen A, Liu S, Geisler BP, Wasem J, Biermann-Stallwitz J. "Clinical and Economic Benefits of Upper Airway Stimulation for Obstructive Sleep Apnea in a European Setting," Respiration.

Geisler BP, Jilg N, Patton RG, Pietzsch JB. "A Model to Evaluate the Impact of Hospital-Based Interventions Targeting False-positive Blood Cultures on Economic and Clinical Outcomes," Journal of Hospital Infection.

Peiffer V, Yock CA, Yock PG, Pietzsch JB. "Value-Based Care: A Review of Key Challenges and Opportunities Relevant to Medical Technology Innovators," Journal of Medical Devices.


Schaefer A, Lubos E, Pietzsch JB, Pietzsch M, Weber S, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L. "Insights from eight years of adoption experience of transcatheter mitral valve repair in Germany: observed utilisation patterns and impact on overall mitral valve procedure volumes," EuroIntervention.

Pietzsch JB, Busca R, Rott C, Geisler BP, Weber SA, Slebos DJ, Deslee G, Herth FJF. "Adoption Patterns of Bronchoscopic Lung Volume Reduction Procedures in Germany and Predicted Procedure Volumes for Other European Countries," Respiration.

Perl L, Peiffer V, Fuhrer A, D’Ascenzo F, Pietzsch JB. "Sex differences in discharge destination following acute myocardial infarction," Coronary Artery Disease.

Pietzsch JB, Weber SA, Lund N, Gaul C. "Changes in Medication Cost Observed in Chronic Cluster Headache Patients Treated with Sphenopalatine Ganglion (SPG) Stimulation: Analysis Based on 1-Year Data from the Pathway R-1 Registry," Cephalalgia.

Faucett SC, Geisler BP, Chahla J, Krych AJ, Kurzweil PR, Garner AM, Liu S, LaPrade RF, Pietzsch JB. "Meniscus Root Repair vs Meniscectomy or Nonoperative Management to Prevent Knee Osteoarthritis after Medial Meniscus Root Tears: Clinical and Economic Effectiveness," Am J Sports Med.


Geisler, BP, Huygens, SA, Reardon, MJ, Van Mieghem, N, Kappetein, AP, Osnabrugge, RLJ, Pietzsch JB. "Cost-Effectiveness and Projected Survival of Self-Expanding Transcatheter Versus Surgical Aortic Valve Replacement for High Risk Patients in a European Setting. A Dutch Analysis Based on the CoreValve High-Risk Trial,"Structural Heart.

Pietzsch, JB, Geisler, BP, Ikeno, F. "Cost‑Effectiveness of Orbital Atherectomy Compared to Rotational Atherectomy in Treating Patients with Severely Calcified Coronary Artery Lesions in Japan," Cardiovascular Interventions and Therapeutics.

Feller-Kopman, D, Liu, S, Geisler, BP, DeCamp, MM, Pietzsch, JB. "Cost-Effectiveness of a Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer," Journal of Thoracic Oncology.


Feeley BT, Liu S, Garner AM, Zhanga AL, Pietzsch JB. “The Cost-Effectiveness of Meniscal Repair Versus Partial Meniscectomy: A Model-Based Projection for the United States,” Knee.

Feller-Kopman DJ, Liu S, Garner AM, Decamp M, Pietzsch JB. "Cost-Effectiveness Of The Percepta Bronchial Genomic Classifier For The Diagnostic Evaluation Of Lung Cancer: An Analytical Framework Based On The AEGIS Studies," ATS Journals.

Geisler B, Osnabrugge R, Huygens S, Reardon M, Kappetein A, Pietzsch J. "Cost-Effectiveness of TAVI vs. Surgical Aortic Valve Replacement: The CoreValve High Risk Trial from a European Perspective," EuroIntervention.

Katsanos K, Geisler BP, Garner AM, Zayed H, Cleveland T, Pietzsch JB. “Economic Analysis of Endovascular Drug-Eluting Treatments for Femoropopliteal Artery Disease in the UK,” BMJ Open.

Noblett NL, Dmochowski RR, Vasavada SP, Garner AM, Liu S, Pietzsch JB. “Cost Profiles and Budget Impact of Rechargeable Versus Non-Rechargeable Sacral Neuromodulation Devices in the Treatment of Overactive Bladder Syndrome,” Neurourology and Urodynamics.

Pietzsch J, Geisler B, Schmieder R, Egan B. "Cost-Effectiveness Threshold Analysis of Various Age and Systolic Blood Pressure Reduction Scenarios for Renal Denervation Therapy," EuroIntervention.

Pietzsch JB, Garner AM, Marks WJ. "Cost-Effectiveness of Deep Brain Stimulation for Advanced Parkinson's Disease in the United States," Neuromodulation.


Busca R, Geisler BP, Pietzsch JB. “Cost-Effectiveness of Transcatheter Aortic Valve Replacement: Current Decision-Analytic Models and Future Opportunities,” Value Health.

Martinsen BJ, Weber SA, Pietzsch ML, Behrens A, Weatherspoon M, Igyarto Z, Zhao R, Kotlarz H, Pietzsch JB. “Economic study design for the optimize study on orbital atherectomy and drug-coated balloon devices for the treatment of below-the-knee peripheral arterial disease,” Value Health.

Pietzsch JB, Busca R, Geisler BP. “Adoption of Transcatheter Aortic Valve Replacement in Germany: Utilization Patterns and Case Volumes Compared to Surgical Aortic Valve Replacement in the Period 2009-2013,” Value Health.

Pietzsch JB, Garner A, Gaul C, May A. “Cost-Effectiveness of Stimulation of the Sphenopalatine Ganglion (Spg) for the Treatment of Chronic Cluster Headache: A Model-Based Analysis Based on the Pathway Ch-1 Study,” The Journal of Headache and Pain.

Pietzch JB, Geisler BP, Zeller T. “Endovascular Interventions for Treatment of Femoropopliteal Peripheral Artery Disease: Updated Budget Impact Analysis for Germany Based on Latest Clinical Evidence,” Value Health.

Pietzsch JB, Liu S, Garner AM, Kezirian EJ, Strollo PJ. “Long-Term Cost-Effectiveness of Upper Airway Stimulation for the Treatment of Obstructive Sleep Apnea: A Model-Based Projection Based on the STAR Trial,” Sleep.

Riskin L, Koppel R, Riskin D. “Re-Examining Health It Policy: What Will it Take to Derive Value from Our Investment?Journal of the American Medical Informatics Association.


Pietzsch JB, Garner A, Herth FJ. “Cost-Effectiveness of Endobronchial Valve Therapy for Severe Emphysema: A Model-Based Projection Based on the Vent Study,” Respiration.

Pietzsch JB, Geisler BP, Garner AM, Zeller T, Jaff MR. “Economic Analysis of Endovascular Interventions for Femoropopliteal Arterial Disease: A Systematic Review and Budget Impact Model for the United States and Germany,” Catheterization and Cardiovascular Interventions: Official Journal of the Society for Cardiac Angiography & Interventions.


Gottlieb S, Makower J. “A Role for Entrepreneurs: An Observation on Lowering Healthcare Costs Via Technology Innovation,” American Journal of Preventative Medicine.

Sasportas LS, Hosford DN, Sodini MA, Waters DJ, Zambricki EA, Barral JK, Graves EE, Brinton TJ, Yock PG, Le QT, Sirjani D. “Cost-Effectiveness Landscape Analysis of Treatments Addressing Xerostomia in Patients Receiving Head and Neck Radiation Therapy,” Oral Surgery, Oral Medication, Oral Pathology and Oral Radiology.


Geisler BP, Egan BM, Cohen JT, Garner AM, Akehurst RL, Esler MD, Pietzsch JB. “Cost-Effectiveness and Clinical Effectiveness of Catheter-Based Renal Denervation for Resistant Hypertension,” Journal of the American College of Cardiology.


Pietzsch JB, Garner A, Cipriano LE, Linehan JH. “An Integrated Health-Economic Analysis of Diagnostic and Therapeutic Strategies in The Treatment Of Moderate-To-Severe Obstructive Sleep Apnea,” Sleep.


Arrow K, Auerbach A, Bertko J, Brownlee S, Casalino LP, Cooper J, Crosson FJ, Enthoven A, Falcone E, Feldman RC, Fuchs VR, Garber AM, Gold MR ,Goldman D, Hadfield GK, Hall MA, Horwitz RI, Hooven M, Jacobson PD, Jost TS, Kotlikoff LJ, Levin J, Levine S, Levy R, Linscott K, Luft HS, Mashal R, McFadden D, Mechanic D, Meltzer D, Newhouse JP, Noll RG, Pietzsch JB, Pizzo P, Reischauer RD, Rosenbaum S, Sage W, Schaeffer LD, Sheen E, Silber BM, Skinner J, Shortell SM, Thier SO, Tunis S, Wulsin L Jr, Yock P, Nun GB, Bryan S, Luxenburg O, van de Ven WP. “Toward a 21st-Century Health Care System: Recommendations for Health Care Reform,” Annals of Internal Medicine.


Pietzsch JB, Paté-Cornel ME. “Early Technology Assessment of New Medical Devices,” International Journal of Technology Assessment in Healthcare.